Dectin-1-activated dendritic cells: A potent Th9 cell inducer for tumor immunotherapy
نویسندگان
چکیده
منابع مشابه
Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells
Dectin-1 signalling in dendritic cells (DCs) has an important role in triggering protective antifungal Th17 responses. However, whether dectin-1 directs DCs to prime antitumour Th9 cells remains unclear. Here, we show that DCs activated by dectin-1 agonists potently promote naive CD4(+) T cells to differentiate into Th9 cells. Abrogation of dectin-1 in DCs completely abolishes their Th9-polariz...
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ژورنال
عنوان ژورنال: OncoImmunology
سال: 2016
ISSN: 2162-402X
DOI: 10.1080/2162402x.2016.1238558